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RFFL Antibody
Phsopho-PKCa (pT638)
6-TAMRA [6-Carboxytetramethylrhodam
[VIP第1年] 指数:3
通过沈阳市浑南区市场监督管理局认证 
Wnt-11
CTNNG/γ-Catenin/JUP
GAPDH
10%SDS
P-JAK2（Tyr1007/1008
细胞增殖MTT/CCK-8
HUVEC
SH-SY5Y| 货号： | WL01996 |
| 抗体名： | Occludin抗体 |
| 抗体英文名： | Occludin |
| 浓度： | >1mg/ml |
| 应用范围： | WB,IHC |
| 宿主： | 兔 |
| 适应物种： | H,M,R |
| 标记物： | 无 |
| 克隆性： | 否 |
| 保存条件： | -20℃ |
| 形态： | 液体 |
| 亚型： | IgG |
| 规格： | 50μl(>50μg) |
本公司所有一抗，50μl(>50μg)现价450元/支，全部现货，均提供20μl免费试用装，详情请点击免费试用
| 产品货号 | WL01996 | |||
| 产品名称 | Occludin Antibody | |||
| 预测分子量 | 60-82kDa | |||
| 别名 | OCLN; BLCPMG; Tight junction protein occludin | |||
| 浓度 | ＞1 mg/ml | |||
| 免疫原 | Occludin重组蛋白 | |||
| 抗体来源 | 兔 | |||
| 特异性 | 抗人,小鼠，大鼠 | |||
| 克隆类型 | 多克隆抗体 | |||
| 产品应用 | WB;IHC | |||
| 成分 | 亲和纯化抗体，20 mM PBS，150 mM NaCl，100 μg/ml BSA，50%甘油，NaN3<0.02% | |||
| 保存条件 | -20℃保存 | |||
| 背景资料 | Occludin is an integral membrane protein closely associated with the tight junctions of epithelial and endothelial cells. Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of occludin. Expression of occludin is up-regulated by polyunsaturated fatty acids, increasing transendothelial cell resistance and reducing cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction. | |||
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温馨提示：不可用于临床治疗。
