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组织蛋白酶B(CTSB)抑制剂筛选试剂盒(荧光法)

产品价格: ¥6675.00

最小起订量:暂无 可售数量:999盒

发货时限:
暂无
所在地区:
中国北京
有效期至:
长期有效
最后更新:
2021-04-22 01:30:02
浏览次数:
61

产品详情

品牌名称:
biovision
货号: K147-100
保存条件: -20度
供应商: 北京博迈斯
英文名: Cathepsin B (CTSB) Inhibitor Screening Kit (Fluorometric)
规格: 100 assays


Assay Kit Name:
Cathepsin B (CTSB) Inhibitor Screening Kit (Fluorometric)

Kit Summary:
• Detection method - Fluorescence (Ex/Em = 400/505 nm)
• Applications - Screen/study/characterize potential inhibitors of Cathepsin B.

Features & Benefits:
• Simple & convenient
• High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin B
• Cathepsin B inhibitor, F-F-FMK is included in the kit

Kit Components:
• CTSB Reaction Buffer
• CTSB Reagent
• Cathepsin B (human)
• CTSB Substrate, Ac-RR-AFC (10 mM)
• CTSB Inhibitor (F-F-FMK, 1 mM)

Description:
Cathepsin B (CTSB, EC 3.4.22.1) is a lysosomal cysteine proteinase that is suggested to participate in intracellular degradation and turnover of proteins. It has also been implicated in tumor invasion and metastasis. Biovision’s Cathepsin B Inhibitor Screening Kit utilizes the ability of Cathepsin B to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin B-specific inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize the potential inhibitors of Cathepsin B.

Storage Conditions:
-20°C

Shipping Conditions:
gel pack

USAGE: For Research Use Only! Not For Use in Humans.

温馨提示:不可用于临床治疗。

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