大鼠/小鼠脑缺血MCAO模型尼龙栓线／尼龙线栓／硅胶栓线／硅胶线栓

MCAO栓线简介

国内最早实行规模化、标准化、商品化的MCAO栓线（有本网站的点击量和发表论文为证）。MCAO栓线是制备大鼠/小鼠（或其它实验动物）局部脑缺血模型的非常关键的实验材料，本产品是用柔韧适度的单丝尼龙线，经显微操作烧制而成，其头端光滑、大小一致，易进入颅内又不至于刺破血管，使用本产品可大大提高模型制备的成功率，及脑缺血范围的稳定性。本产品已被美国、加拿大、香港、中国大陆等的科研机构、大学、医院广泛采用。研究论文发表于本专业顶级的期刊：J Neuroscience，Stroke，Journal of Cerebral Blood，Flow & Metabolism，Journal of Neurochemistry等（见附录）。

产品分五个级别，每个级别分若干型号和规格。（见MCAO栓线型号/价格表）

A1级：头端烧熔为半球形（图1），无包被、无标记、未消毒，需要用户自己消毒、做标记；

A2级：头端烧熔为半球形，无包被、有标记*、已消毒，可以直接使用；

A3级：头端烧熔为半球形，前端包被多聚赖氨酸^#、无标记、已消毒，需要用户自己做标记；

A4级：头端烧熔为半球形，前端包被多聚赖氨酸、有标记、已消毒，即买即用型，不需任何处理。

A5级：头端烧熔为半球形，且前端5-6mm均匀包被硅橡胶（图2），有标记、已消毒，即买即用型，不需任何处理。包被硅胶的直径及对应的动物体重见附表。如客户订做小鼠的新型号硅胶线（指硅胶直径>0.22的型号），则每次最少10根/400元，如超过30根，仍按35元/根；如客户订做大鼠的新型号硅胶线（指硅胶直径>0.28的其它型号），则每次最少10根/300元，如超过30根，仍按25元/根。A5栓线插线操作相对难于其它级别，建议预实验时，另选一个相邻的较小体重级别的型号，如大鼠体重为240-270g，除了选2634型号的硅胶线，最好再选一个对应200-240g体重的型号。另外还可以选硅胶长度为3-4mm的硅胶线，相对好操作一些。

* 大鼠线栓的标记在距头端19-20mm处，小鼠线栓的标记在距头端9-10mm处.

^# 前端20mm(大鼠线栓)或10mm(小鼠线栓)包被多聚-L-赖氨酸（包被多聚-L-赖氨酸不会改变栓线的直经）。栓线包被多聚-L-赖氨酸，可以提高MCAO模型的稳定性。

MCAO栓线型号/价格表（请询价）

 附录：使用我们的MCAO栓线最近发表的部分SCI英文论文

（论文中的“Beijing Sunbio Biotech Co. Ltd.”既是西浓科技的前身）

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