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Anti-DND1抗体

产品价格: ¥1380.00

最小起订量:暂无 可售数量:暂无

发货时限:
暂无
所在地区:
全国
有效期至:
长期有效
最后更新:
1970-01-01 08:00:00
浏览次数:
33

产品详情

品牌名称:
Ybscience

 Anti-DND1抗体

产品编号 YB-14397R
英文名称 DND1
中文名称 DND1蛋白抗体
别    名 Dead end homolog 1 (zebrafish); Dead end protein; Dead end protein homolog 1; dnd1; DND1_HUMAN; MGC34750; RBMS4; RNA binding motif single stranded interacting protein 4; RNA-binding motif; single-stranded-interacting protein 4; Ter.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  细胞生物  发育生物学  干细胞  结合蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
细胞定位 细胞核 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DND1:51-150/353 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background: This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17. [provided by RefSeq, Dec 2010] Function: RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3 untranslated region (3-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration. Subcellular Location: Nucleus. Cytoplasm. Perinuclear germ granules, also called germ plasm or chromatoid body. Colocalizes in perinuclear sites with APOBEC3. Similarity: Contains 2 RRM (RNA recognition motif) domains. SWISS: Q8IYX4 Gene ID: 373863 Database links:

Entrez Gene: 373863 Human

Entrez Gene: 213236 Mouse

Entrez Gene: 679841 Rat

Omim: 609385 Human

SwissProt: Q8IYX4 Human

SwissProt: Q6VY05 Mouse

Unigene: 591262 Human

Unigene: 234464 Mouse

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.   
产品图片
Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DND1) Polyclonal Antibody, Unconjugated (bs-14397R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining

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