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Anti-HOOK3抗体

产品价格: ¥1380.00

最小起订量:暂无 可售数量:暂无

发货时限:
暂无
所在地区:
全国
有效期至:
长期有效
最后更新:
1970-01-01 08:00:00
浏览次数:
18

产品详情

品牌名称:
Ybscience

 Anti-HOOK3抗体

产品编号 YB-17355R
英文名称 HOOK3
中文名称 HOOK3蛋白抗体
别    名 FLJ31058; h-hook3; hHK3; HK3; hook3; HOOK3_HUMAN; OTTHUMP00000229200; Protein Hook homolog 3.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  信号转导  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量 83kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HOOK3:481-580/718 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background: Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004] Function: Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. Subcellular Location: Cytoplasm > cytoskeleton. Golgi apparatus. Enriched at the cis-face of the Golgi complex (By similarity). Localizes to microtubule asters in prophase. Similarity: Belongs to the hook family. SWISS: Q86VS8 Gene ID: 84376 Database links:

Entrez Gene: 84376 Human

Entrez Gene: 320191 Mouse

Entrez Gene: 306548 Rat

Omim: 607825 Human

SwissProt: Q86VS8 Human

SwissProt: Q8BUK6 Mouse

Unigene: 162852 Human

Unigene: 334464 Mouse

Unigene: 203282 Rat

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.   
产品图片
Sample:  Small intestine(Mouse) Cell Lysate at 40 ug Primary: Anti-HOOK3(bs-17355R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 83 kD Observed band size: 83 kD

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