点击图片查看原图

Anti-LMBRD1抗体

产品价格: ¥1380.00

最小起订量:暂无 可售数量:暂无

发货时限:
暂无
所在地区:
全国
有效期至:
长期有效
最后更新:
2021-05-25 01:30:01
浏览次数:
60

产品详情

品牌名称:
Ybscience

 Anti-LMBRD1抗体

产品编号 YB-18309R
英文名称 LMBRD1
中文名称 核输出信号相互作用蛋白抗体
别    名 HDAg-L-interacting protein NESI; LMBD1_HUMAN; LMBR1 domain-containing protein 1; lmbrd1; Nuclear export signal-interacting protein; Probable lysosomal cobalamin transporter.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  细胞生物  免疫学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LMBRD1:21-120/540 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background: This gene encodes a lysosomal membrane protein that may be involved in the transport and metabolism of cobalamin. This protein also interacts with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F.[provided by RefSeq, Oct 2009] Function: Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV). Subcellular Location: Lysosome membrane. Tissue Specificity: Isoform 3 is expressed in liver. Post-translational modifications: N-glycosylated. DISEASE: Defects in LMBRD1 are the cause of methylmalonic aciduria and homocystinuria type cblF (MMAFHC) [MIM:277380]; also known as homocystinuria-megaloblastic anemia complementation type F. MMAFHC is a disorder of cobalamin metabolism characterized by decreased levels of the coenzymes adenosylcobalamin (AdoCbl) and methylcobalamin (MeCbl). It is due to accumulation of free cobalamin in lysosomes, thus hindering its conversion to cofactors. Clinical features include developmental delay, stomatitis, glossitis, seizures and methylmalonic aciduria responsive to vitamin B12. Similarity: Belongs to the LIMR family. LMBRD1 subfamily. SWISS: Q9NUN5 Gene ID: 55788 Database links:

Entrez Gene: 55788 Human

Entrez Gene: 68421 Mouse

Entrez Gene: 246046 Rat

Omim: 612625 Human

SwissProt: Q9NUN5 Human

SwissProt: Q8K0B2 Mouse

SwissProt: Q6AZ61 Rat

Unigene: 271643 Human

Unigene: 677072 Human

Unigene: 477783 Mouse

Unigene: 201860 Rat

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.   
产品图片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LMBRD1) Polyclonal Antibody, Unconjugated (bs-18309R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining

免责声明

本网页所展示的有关【Anti-LMBRD1抗体】的信息/图片/参数等由的会员【 】提供,由【生物实验采购网】会员【 】自行对信息/图片/参数等的真实性、准确性和合法性负责,本平台(本网站)仅提供展示服务,请谨慎交易,因交易而产生的法 律关系及法律纠纷由您自行协商解决,本平台(本网站)对此不承担任何责任。您在本网页可以浏览【Anti-LMBRD1抗体】有关的信息/图片/价格等及提供 【Anti-LMBRD1抗体】的商家公司简介、联系方式等信息。

在您的合法权益受到侵害时,请您致电,我们将竭诚为您服务,感谢您对【生物实验采购网】的关注与支持!

网站首页 | 关于我们 | 联系方式 | 使用协议 | 版权隐私 | 网站地图  |  排名推广  |  广告服务  |  积分换礼  |  网站留言  |  RSS订阅  |  违规举报
 
免责声明:本站有部分内容来自互联网,如无意中侵犯了某个媒体 、公司 、企业或个人等的知识产权,请来电或致函告之,本网站将在规定时间内给予删除等相关处理。