货号: | L5000 |
供应商: | TargetMol中国 |
数量: | 500万 |
英文名: | Diversity Compound Library |
保质期: | 干粉三年 |
保存条件: | -20°C |
TargetMol分子库可用于细胞信号通路和细胞诱导的实验,以及药物研究相关的应用,例如高通量和高内涵药物筛选等。
我们的分子库涵盖了 500万种多样性小分子和3000种以上的 有生物活性小分子,是独特且多样的,相关的化合物化学信息和活性信息齐全,广泛应用于高通量筛选、高内涵筛选, 及生化方面的研究等。这些独特小分子化合物主要作用于20多个信号通路中的200多个靶点,如GPCR,PI3K,Akt及凋亡通路等。我们公司提供每组产品的化学信息,生物活性,及化学特性等等。
高通量筛选库;高通路药物筛选库;HTS library;多样性化合物库;Diversity Compound Library
Chemical Libraries and Screening Compounds
During the course of our synthetic and screening endeavors, we have identified a range of approaches to both diverse and highly specialized (focused) compound selections. These libraries have been extensively validated in our in-house biological assays as well as in the laboratories of over 200 external partners including Pharma, Biotech, Academia and Screening Centers in the U.S., Europe and Japan. Currently, we offer a shelf-available set of over 5 M individual solid screening compounds. A custom selection that suits your specific screening needs could be dispatched in any custom format to you within 2-3 weeks.
Our computational, structural biology, synthetic and medicinal chemistry team follow current trends in modern structure-based drug discovery to add novel diverse and targeted compounds. The latter selections are aimed at tackling multiple targets, protein domains, pathways, cellular processes, etc. Representative examples of these biased libraries include modulators of numerous protein-protein interactions, stem cell differentiation, apoptosis, proteasome cascade including diverse ligases, autophagy, epigenetics machinery, cell cycle including quiescent cancer cells, motor proteins, mitochondrial homeostasis and cell energetic, viral targets, bacterial genome, protein folding machinery including scaffolding proteins and chaperones and many others. We have also assembled screening sets for agrochemical, cosmetics and food industries reflective of the Generally Recognized As Safe (GRAS) concepts.
Contains ChemDiv, Enamine, Life Chemicals, Chembridge, and other well-known brands.
定制流程
陶素生化科技有限公司为美国Target Molecule Corp. ( Target Mol ) 在上海建立的全资子公司。我们与美国波士顿、德国慕尼黑的同事一起,为北美、欧洲和亚洲从事药物研发和生物学研究的科学家提供优质的产品和专业的服务。公司下设四个事业部,筛选事业部,化学事业部,生物事业部和材料事业部。可以为客户提供从虚拟筛选到实体化合物分子供应;从商业化产品销售到个性化定制合成;从对明确靶点的分子筛选到对明确分子的多靶点筛选,从高通量筛选到化学结构优化,我们都可以满足您对应的科研用品以及技术服务的需求。
如果您是如下领域的客户,我们将有机会与您合作,助您科研一臂之力。
药物筛选:药物设计及模拟筛选,靶点确认,模型建立,高通量筛选,高内涵筛选,结构优化。
药理学研究:从细胞实验到动物实验的阳性化合物对照,已知药物的新用途研究。
信号通路:Stem Cell,GPCR,Protein Tyrosine Kinase,Metabolism,Epigenetics等各种热门信号通路的活性小分子抑制剂。
细胞研究:诱导多功能干细胞的相关研究,或者是作为工具进行相关的细胞学实验。
陶素作为筛选化合物库供应平台已经和中国科学院,北京大学,复旦大学,国家新药筛选中心,中国药科大学,中山大学,四川大学,第二军医大学和南方医科大学等科研机构以及强生,恒瑞,先声等制药企业提供了品质卓越的小分子筛选化合物库,我们期待着和越来越多的客户建立更多的联系与合作。
合作品牌:独家代理ChemDiv,TaregtMol,一级代理microsource,IBS等"
TargetMol其他更多特色化合物库:
上市药物库HOT Approved Drug Library | 抑制剂库HOT Inhibitor Library | 已知活性库HOT Bioactive Compound Library | 天然产物库HOT Natural Compound Library |
CADD靶点库 CADD Target Library | 临床药物库HOT Clinical Compound Library | FDA上市药物库HOT FDA-approved Drug Library | 杂质精选库 |
干细胞分化小分子库 Stem cell Differentiation Compound Library | 抗感染库 Anti-infection Compound library | 细胞凋亡化合物库 Apoptosis Compound Library | 自噬化合物库 Autophagy Library |
高通量筛选库 | 内分泌化合物库 Endocrinology-Hormones Library | 表观遗传化合物库 Epigenetics Inhibitor Library | 组胺化合物库 Histamine &melatonin Library |
内源性代谢小分子库 Human Endogenous Metabolize Compound Library | 离子通道抑制剂库 Ion Channel Inhibitor Library | MAPK抑制剂库 MAPK Inhibitor Library | 氧化还原化合物库 Oxidation-Reduction Compound Library |
PI3K/Akt/mTOR化合物库 PI3K/Akt/mTOR Compound Library | 蛋白酶体抑制剂库 Protease Inhibitor Library | 5羟色胺化合物库 Serotonin Library | 造血毒性化合物库 Hematopoietic Toxicity Compound Library |
酪氨酸激酶抑制剂库 Tyrosine kinase inhibitor library | 抗病库化合物库 Anti-virus Compound library | 抗糖尿病库 Anti-diabetic Compound Library | 抗炎化合物库 Anti-inflammation library |
抗生素库 Antibiotics Library | 抗真菌化合物库 Antifungal Compound Library | 植物来源精选天然产物库Selected plant-sourced compound library | DNA修复与损伤库 DNA Damage & Repair Library |
细胞因子抑制剂库 Cytokines inhibitors library | 激酶抑制剂库 Kinase Inhibitors library | GPCR化合物库 GPCR Compound Library | 活性脂质化合物库 Bioactive Lipid Inbibitor Library |
抗癌上市药物库 Anti-cancer approved drug library | 抗癌临床药物库 Anti-cancer clinical drug library | 心脏毒性化合物库 Cardiotoxicity Compound Library | 肾上腺素库 Adrenergic Library |
抗代谢疾病库 Anti-Metabolism disease Compound Library | 线粒体靶向化合物库 Mitochondrial Targeting Compound Library | 抗心血管疾病化合物库 Anti-Cardiovascular disease Compound Library | 多酚天然产物库 Polyphenolic Natural compound Library |
血管再生化合物库 Angiogenesis related compound library | 毒物化合物库 Killer collections | 片段库 Fragment compounds library | 骨架化合物库 |
抗癌库 Anti-cancer Library | CNS化合物库 CNS Compound Library |