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Anti-MBL (human)

产品价格: ¥595.00

最小起订量:暂无 可售数量:暂无

发货时限:
暂无
所在地区:
中国上海
有效期至:
长期有效
最后更新:
2018-03-20 18:41:34
浏览次数:
26

产品详情

品牌名称:
BioPorto
货号: HYB 131-102
抗体名: Anti-MBL (human)
抗体英文名: Anti-MBL (human)
靶点: 见官方网站
浓度: 1 mg/ml
应用范围: ELISA, WB
宿主: Human
供应商: 上海泽叶生物科技有限公司
数量: 30
级别: 见官方网站
目录编号: HYB 131-102
抗原来源: 见官方网站
保质期: 1年
适应物种: 见官方网站
标记物: 见官方网站
克隆性:
保存条件: -20ºC
形态: 冻干粉或液体
亚型: 见官方网站
免疫原: 见官方网站
规格: 200ug

Anti-MBL (human)

Bioporto是一家体外诊断公司,专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。
官方网站:www.bioporto.com
Cat. No.
HYB 131-102
Product name
Anti-MBL (human)
Description

Mouse monoclonal antibody

Specificity

HYB 131-10 is specific for MBL (mannan-binding lectin) from human serum or plasma.

Immunogen

MBL purified from human donor plasma.

Application
ELISA, WB
Species reactivity (positive)
Human
Species reactivity (negative)
Not determined
Subclass

IgG1/k

Gene ID
4153
Clone number
1E2
Epitope

The epitope is thought to be on the carbohydrate recognition domain and differs from that of HYB 131-01 and HYB 131-11.

Content

Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification
Protein-A purified
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target

Mannan-binding lectin (MBL), also called mannose-binding lectin or protein, belongs to the C-type family of collectins, showing calcium-dependent binding to certain sugars (1). It consists of oligomers of triple-chain subunits and its binding and complement activating activities depend on its normal oligomerization. On binding to mannan-like microbial surface carbohydrates, MBL activates the complement system by means of its own lectin pathway, depending on the MBL-associated serine proteases (MASPs). Because of the presence of different structural and promoter alleles in the population, 12% or more of the population have low concentrations (<50ng/mL) of normally oligomerized, functional MBL in plasma or serum.

Application 1

ELISA

HYB 131-10 reacts strongly with MBL. Strong reaction is seen in ELISA with MBL coated directly onto the microtiter well. In Western blotting HYB 131-10 reacts with human MBL in both its oligomerized state and as single protein chain of 26 kDa. HYB 131-10 can be used to measure MBL in plasma or serum but is not specific for oligomerized MBL when used in combination with itself or other MBL antibodies(1).
Application 2

WB

HYB 131-10 can be used in Western blotting.
温馨提示:不可用于临床治疗。

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