货号: | 20182164 |
供应商: | 上海三抒生物科技有限公司 |
数量: | 咨询 |
英文名: | human MX1 Protein |
保质期: | 咨询 |
保存条件: | -20℃ |
规格: | 100ug |
human MX1 Recombinant Protein
Gene Symbol::MX1
Official Gene Full Name:MX dynamin like GTPase 1
NCBI Gene Id:4599
Alias Symbols:
IFI78, IFI-78K, Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA, MX, MxA, Myxoma resistance protein 1, Myxovirus resistance protein 1
Description Of Target:
Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.1
Swissprot Id:P20591
Protein Accession #:NP_001138397.1
Nucleotide Accession #:NM_001144925.2
Host: E.coli
Conjugation: Unconjugated
Protein Name: Interferon-induced GTP-binding protein Mx1
Molecular Weight: 31 kDa
Tissue Tool: Find tissues and cell lines supported by DNA array analysis to express MX1.
RNA Seq: Find tissues and cell lines supported by RNA-seq analysis to express MX1.
Product Format: Lyophilized
Species Reactivity: Human
Formulation: Lyophilized in PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Purity: > 95%
Source: Prokaryotic Expressed Recombinant
Application: SDS-PAGE, WB, ELISA, IP
Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Residues: Ser80 - Leu342
Subcellular Location: Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic si
Tag: N-terminal His Tag
Reconstitution And Storage: Reconstitute in PBS or others.
Store at 2-8C for one month. Aliquot and store at -80C for 12 months. Avoid repeated freeze/thaw cycles.
Datasheets / Downloads: Printable datasheet for SS05478