Cynomolgus LAG-3 / CD223 Protein, Mouse IgG2a Fc Tag

货号：	LA3-C52A0
供应商：	ACROBiosystems
数量：	In Stock
英文名：	Cynomolgus LAG-3 / CD223 Protein, Mouse IgG2a Fc Tag
规格：	100ug

内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>85% as determined by SDS-PAGE.

活性:
Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus LAG-3, mouse IgG2a Fc tag (Catalog # LA3-C52A0) at 2 μg/mL (100 μL/well) can bind Anti-LAG3 MAb,Human IgG1 with a linear range of 3-20 ng/mL.

产品背景:
Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

产品描述:
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 73.7 kDa. The protein migrates as 78-92 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
 

SDS-PAGE

Cynomolgus LAG-3 / CD223, Mouse IgG2a Fc Tag on SDS-PAGE  under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.
 

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