Human LILRB2 / CD85d / ILT4 Protein, Fc tag

货号：	CDD-H5259
供应商：	ACROBiosystems
数量：	In Stock
英文名：	Human LILRB2 / CD85d / ILT4 Protein, Fc tag
规格：	100ug/1mg

内毒素:
Less than 1.0 EU per μg by the LAL method.

纯度:
>85% as determined by SDS-PAGE.

活性:
Measured by its binding ability in a functional ELISA. Immobilized Human ANGPTL7, His Tag at 5 μg/mL (100 μL/well) can bind Human LILRB2, Fc Tag (Catalog # CDD-H5259) with a linear range of 0.031-2 μg/mL.

产品背景:
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

产品描述:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 74.4 kDa. The protein migrates as 110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
 

SDS-PAGE

Human LILRB2, Fc tag on SDS-PAGE  under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.