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Anti-Mouse CTLA-4 Antibody (MCT.F6), mAb, Mouse 

产品价格: ¥990.00

最小起订量:暂无 可售数量:暂无

发货时限:
暂无
所在地区:
中国江苏南京市
有效期至:
长期有效
最后更新:
2021-05-29 01:30:05
浏览次数:
25
企业信息

产品详情

品牌名称:
GenScript
货号: A01842-40
抗体名: 一抗
抗体英文名: Primary Antibodies 
浓度: Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
宿主: Mouse
克隆性:
保存条件: The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles.
亚型: MCT.F6
免疫原: Recombinant mouse CTLA-4-Fc
规格: 40μg 
Cytotoxic T-lymphocyte-associated protein 4 (CTLA4), also known as CD152, is one of the first well studied immune checkpoint molecules. CTLA4 is expressed on T cells and its expression level can be up-regulated after T cell activation. CTLA4 has two ligands CD80 (B7-1) and CD86 (B7-2). CTLA4 can compete with CD28 binding with these two ligands and transmits an inhibitory signal to T cells. Therapeutic antibodies against CTLA4 can help to stimulate T cells which can then target many cancer cells. Mouse CTLA-4 antibodies with has blocking effect against CD80/CD86 binding with CTLA4 can serve as a great surrogate antibody in mouse model.
GenScript Anti-Mouse CTLA-4 Antibody (MCT.F6), mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from mouse immunized with recombinant mouse CTLA4-Fc
温馨提示:不可用于临床治疗。

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