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Anti-Active Rab7 Mouse Monoclonal Antibody

产品价格: ¥4800.00

最小起订量:暂无 可售数量:暂无

发货时限:
暂无
所在地区:
中国湖北武汉市
有效期至:
长期有效
最后更新:
2021-03-25 01:30:01
浏览次数:
24

产品详情

品牌名称:
NewEastBio
货号: 26923
抗体名: Rab7
抗体英文名: Rab7-GTP antibody
靶点: Rab7
浓度: 1mg/ml
应用范围: IP、IHC、IF
宿主: Mouse
供应商: NewEastBio
数量: 30000
级别: 实验级
目录编号: 26923
抗原来源: Mouse
保质期: 两年
适应物种: 脊椎动物
标记物: FITC
克隆性:
保存条件: -20℃
形态: 液体
亚型: IgG
免疫原: Mouse
规格: 30μl
Active Rab7-GTP [26923]
[30 µL]
 
 
Catalog Number:  26923
Gene Symbol:  RAB7
Description:   Anti-Active Rab7 Mouse Monoclonal Antibody
Background:   Rab7 belongs to the Rab family of small GTPases. Rab7 is located in the late endosome, lysosome, cytoplasmic vesicle, phagosome and melanosome. It is involved in the late endocytic transport and contributes to the maturation of phagosomes.
Immunogen:   Recombinant full length protein of active Rab7
Applications:   IP, IHC, IF
Recommended Dilutions:   
1 µg for ~2 mg total cellular proteins for IP 
1:100 dilution for IHC, IF
Concentration:   1 mg/ml
Host:   mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Anti-active Rab7 antibody recognizes active Rab7 proteins of vertebrates.
Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles
 
Immunoprecipitation/Western blot:  
Rab7 activation assay. Purified full-length Rab7 proteins were immunoprecipitated after treated with GDP (lane 1) orGTPγS (lane 2). Immunoprecipitation was done with the anti-active Rab7 monoclonal antibody (Cat. No. 26923). Immunoblot was with an anti-Rab7 polyclonal antibody (Cat. No. 21069).
Publications:
1.  VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors
    Hepatology Volume 61, Issue 1, pages 361–374, January 2015
2.  Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance
    Endocrinology. 2014 Sep;155(9):3315-28
温馨提示:不可用于临床治疗。

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