Anti-Active Rab4 Mouse Monoclonal Antibody_抗体_试剂_供应

Anti-Active Rab4 Mouse Monoclonal Antibody

产品价格: ￥4800.00

最小起订量：暂无可售数量：暂无

发货时限：: 暂无

所在地区：: 中国湖北武汉市

有效期至：: 长期有效

最后更新：: 2021-07-01 01:30:03

浏览次数：: 26

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货号：	26921
抗体名：	Rab4
抗体英文名：	Rab4—GTP
靶点：	Rab4
浓度：	1mg/ml
应用范围：	IP、IHC
宿主：	Mouse
供应商：	NewEastBio
数量：	30000
级别：	实验级
目录编号：	26921
抗原来源：	Mouse
保质期：	两年
适应物种：	脊椎动物
标记物：	FITC
克隆性：	是
保存条件：	-20℃
形态：	液体
亚型：	IgG
免疫原：	Mouse
规格：	30μl

Active Rab4-GTP [26921]
[30 µL]

Catalog Number: 26921

Gene Symbol: RAB4

Description: Anti-Active Rab4 Mouse Monoclonal Antibody

Background: Rab-4 belongs to the small GTPase Rab family. It interacts with RAB11FIP1, RABEP1, ZFYVE20, RUFY1, SGSM1, SGSM2 and SGSM3. It participates in protein transport and in vesicular traffic.

Immunogen: Recombinant full length protein of active Rab4A.

Applications: IP, IHC

Recommended Dilutions: 1 μg for 1~2 mg total cellular proteins for IP
1:50~100 dilution for IHC

Concentration: 1 mg/ml

Host: mouse

Format: Liquid

Clonality: Monoclonal

Isotype: IgG

Purity: Purified from ascites

Storage buffer:

Preservative: no

Constituents: PBS (without Mg²⁺ and Ca²⁺), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity: Anti-active Rab4 antibody recognizes active Rab4 from vertebrates.

Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles

Immunoprecipitation/Western blot:

Rab4A activation assay. Purified GST-tagged Rab4A proteins (Cat. #10130) were immunoprecipitated with the anti-active Rab4 monoclonal antibody (Cat. No. 26921) after treated with GDP (lane 1) or GTP_γ S(lane 2), and was blotted with anti-Rab4A polyclonal antibody (Cat. No. 21067). Input control is shown in the bottom panel.

Publications:

1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors
Hepatology Volume 61, Issue 1, pages 361–374, January 2015

2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance
Endocrinology. 2014 Sep;155(9):3315-28

温馨提示：不可用于临床治疗。

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Anti-Active Rab4 Mouse Monoclonal Antibody

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