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Anti Ga13 Rabbit Polyclonal Antibody

产品价格: ¥2800.00

最小起订量:暂无 可售数量:暂无

发货时限:
暂无
所在地区:
中国湖北武汉市
有效期至:
长期有效
最后更新:
2021-05-23 01:30:07
浏览次数:
13

产品详情

品牌名称:
NewEastBio
货号: 21005
抗体名: 抗Ga13 兔多克隆抗体
抗体英文名: Anti Ga13 Rabbit Polyclonal Antibody
靶点: Ga13
应用范围: WB,IF
宿主:
供应商: NewEastbio
数量: 30
级别: 实验级
目录编号: 21005
抗原来源:
保质期: 1年
适应物种: 脊椎动物
标记物:
克隆性:
保存条件: -20℃
形态: 液体
免疫原: Recombinant full length Gα13 protein
规格: 100ul
Gα13 [21005]
[100 µL]
 
 
Catalog Number:  21005
Gene Symbol:  Ga13
Description:   Anti-Gα13 Rabbit Polyclonal Antibody
Background:   Heterotrimeric G proteins are essential cellular signal transducers. Gα13is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Gα13 are being explored.
Immunogen:   Recombinant full length Gα13 protein
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA 1:100-1:5000
WB 1:100-1:2000
IHC 1:50-1:100
Concentration:   1 mg/ml
Host:   Rabbit
Format:   Liquid
Clonality:   Polyclonal
Isotype:   
Purity:   Purified from serum
Storage buffer:
Preservative:  no
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  13 polyclonal antibody recognizes Gα13 of vertebrates.
Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles
 
Western blot:  
Western blot analysis of Gα13 proteins. MEF whole-cell lysates were used for western blot with anti-Gα13polyclonal antibody (Cat. # 21005).
Immunofluorescence:  
Immunofluorescence of mouse embryonic fibroblast (MEF) cells. Wild-type MEF cells (top panel) and Gα13double knock-out cells (Gα13 -/-, bottom panel) were fixed and stained with anti-Gα13 polyclonal antibody (Cat. # 21005). Arrows indicate the dorsal ruffle strcture of one cell.
Publications:
1.  Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization
    J Biol Chem. 2011 Sep 2;286(35):31055-61
2.  Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Galpha and beta-arrestin-2
    Br J Pharmacol. 2011 Feb;162(3):733-48
3.  Gα12/13 inhibition enhances the anti-cancer effect of bortezomib through PSMB5 downregulation
    Carcinogenesis (2010)
4.  Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency
    J Biol Chem. 2009 Oct 2;284(40):27409-15
温馨提示:不可用于临床治疗。

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