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兔抗小鼠血清
Pacific Blue™ anti-human GM-CSF
1X RBC Lysis Buffer 200 mL
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| 货号： | OAEC04260 |
| 抗体英文名： | MCL1 Antibody (OAEC04260) |
| 靶点： | MCL1 |
| 宿主： | Mouse |
| 适应物种： | Human |
| 克隆性： | 否 |
| 保存条件： | Store at 4C, for long term storage, store at -20C. |
| 形态： | Purified antibody in PBS containing 0.03% sodium azide |
| 亚型： | IgG1 |
| 免疫原： | Purified recombinant fragment of human MCL-1 expressed in EColi |
| 规格： | 100 ug/100 ul |
Swissprot Id: Q07820
Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lym phocytes undergoing apoptosis following treatm ent with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expres sion of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSm yc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatm ent with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lys ate. - See more at: http://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAEC04260
HepG2 cells
Confocal immunofluorescence analysis of HepG2 cells using MCL1 mouse mAb (green). Red. Actin filaments have been labeled with DY-554 phalloidin. Blue. DRAQ5 fluorescent DNA dye.
Human lymphnode tissues
Immunohistochemical analysis of paraffin-embedded human lymphnode tissues using MCL1 mouse mAb with DAB staining.
Hela (1), BCBL-1 (2), Jurkat (3) and HL60 (4) cell lysate
Western blot analysis using MCL1 mouse mAb against Hela (1), BCBL-1 (2), Jurkat (3) and HL60 (4) cell lysate.
温馨提示：不可用于临床治疗。
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